| Paper: | PS-1B.56 | ||
| Session: | Poster Session 1B | ||
| Location: | H Fläche 1.OG | ||
| Session Time: | Saturday, September 14, 16:30 - 19:30 | ||
| Presentation Time: | Saturday, September 14, 16:30 - 19:30 | ||
| Presentation: | Poster | ||
| Publication: | 2019 Conference on Cognitive Computational Neuroscience, 13-16 September 2019, Berlin, Germany | ||
| Paper Title: | Hierarchical network analysis of behavior and neuronal population activity | ||
| Manuscript: | Click here to view manuscript | ||
| License: |  This work is licensed under a Creative Commons Attribution 3.0 Unported License. |
||
| DOI: | https://doi.org/10.32470/CCN.2019.1261-0 | ||
| Authors: | Kevin Luxem, Falko Fuhrmann, Stefan Remy, Pavol Bauer, German Center for Neurodegenerative Diseases, Germany | ||
| Abstract: | Recording of neuronal population activity in behaving animals is becoming increasingly popular. Computational markerless annotation tools allow for tracking of animal body-parts throughout the experiment. However, the question remains of how to cross-correlate the extracted behavioral data with the simultaneously acquired neuronal population activity, when both datasets are of high dimensionality. Here we propose a combined analysis, where the behavioral data is clustered into discrete states using a deep learning model and the occurrence of each state is correlated to clusters of neuronal activity. We then model the relationship between behavioral states as a network, where related states are hierarchically grouped while the similarity between their neuronal correlates is maximized. This type of analysis allows for hierarchical exploration of the bidirectional relationship between behavior and its neuronal correlates at different temporal scales. | ||