| Paper: | PS-1B.2 |
| Session: | Poster Session 1B |
| Location: | H Fläche 1.OG |
| Session Time: | Saturday, September 14, 16:30 - 19:30 |
| Presentation Time: | Saturday, September 14, 16:30 - 19:30 |
| Presentation: |
Poster
|
| Publication: |
2019 Conference on Cognitive Computational Neuroscience, 13-16 September 2019, Berlin, Germany |
| Paper Title: |
Episodic memory retrieval is supported by rapid replay of episode content |
| Authors: |
G. Elliott Wimmer, Yunzhe Liu, Neža Vehar, University College London, United Kingdom; Tim Behrens, University of Oxford, United Kingdom; Raymond J Dolan, University College London, United Kingdom |
| Abstract: |
Episodic memory retrieval entails the reactivation of neural representations that reflect elements of an experience. The characteristics of retrieval and whether and how it is supported by time-compressed reactivation or ‘replay’ of the sequential episode components remain unknown. We studied participants who had been exposed to unique episodes followed by a memory test the next day using magnetoencephalography (MEG). When the goal was to retrieve subsequent elements of an episode, accuracy for weaker memories was supported by reverse sequential replay with a compression factor greater than 60. However, when the goal was to retrieve elements preceding a cue, retrieval was supported instead by forward replay. Replay effects were the strongest in participants with lower mean performance. In participants with strong memories, we found evidence for repeated brief clustered reactivation of episode elements. Our results demonstrate novel mechanisms underlying episodic memory retrieval that inform how the brain constructs world models and how memory may be used in decision making. |
