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Paper Detail

Paper: PS-2A.42
Session: Poster Session 2A
Location: H Lichthof
Session Time: Sunday, September 15, 17:15 - 20:15
Presentation Time:Sunday, September 15, 17:15 - 20:15
Presentation: Poster
Publication: 2019 Conference on Cognitive Computational Neuroscience, 13-16 September 2019, Berlin, Germany
Paper Title: Phase coding of competing memories along the hippocampal theta oscillation in human MEG
Manuscript:  Click here to view manuscript
License: Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 Unported License.
Authors: Casper Kerrén, Maria Wimber, University of Birmingham, United Kingdom
Abstract: How can the human brain retrieve unique memories, given the vast amount of overlapping information available in memory? The aim of the present study is to understand what role hippocampal theta oscillations play in this mnemonic selection process. Computational models propose that phase coding along a slow (theta) oscillation provides an efficient way of separating relevant, to-be-remembered information from overlapping, currently irrelevant information (Lisman & Jensen, 2013; Norman et al., 2006). In the present study, we used a newly developed approach (Kerren, Linde-Domingo, Hanslmayr, & Wimber, 2018) for analysing periodic memory reactivation in non-invasive magnetoencephalographic (MEG) data. We show that to-be-remembered memories are reactivated at a specific phase along a slow (7Hz) hippocampal oscillation, and that the brain codes competing memories at a different phase of the oscillatory cycle. This is the first demonstration of phase shifts in periodic memory reactivation signals in humans, and provides new insights into how the brain handles mnemonic competition on a millisecond time scale.